Clinical Findings
This 49 yr old female had been exposed to sandblasting and 25yrs of cigarettes. On questioning, she admitted to a grinding chest pain, originating in the mid-back and radiating around the left chest into the sub-sternal area. The pain, brought on when walking the dog on cold days and relieved in a few minutes by rest, had not previously been treated or diagnosed. She denied shortness of breath. A physical examination revealed no evidence of peripheral vascular disease, heart murmurs or abnormal heart sounds. The resting 12 lead- ECG was within normal limits.
Exercise Findings
The patient performed exercise on a cycle ergometer. She pedalled at 60rpm without added load for 3 min. The work rate was then increased 10W per minute to his symptom-limited maximum. The patient stopped exercising due to sub-scapular pain and right anterior chest pain. No significant ECG changes. The chest pain resolved within 1 minute of cessation of exercise.
Selected Respiratory Function Data – were all within normal limits
Measurement | Predicted | Measured |
Age, yr | 49 | |
Sex | Female | |
Height, cm | 170 | |
Weight, kg | 80 | |
Hb, g/L | [130-165 g/L] | 110 |
VC, L | 2.56 – 3.92 | 3.63 |
VC, % Predicted | 112 | |
PEF, L | 300.84 – 477.96 | 476 |
FEV1, L | 2.06 – 3.31 | 2.73 |
Selected Exercise Data
Measurement | Predicted | Measured |
Exercise duration | 7:31 | |
Peak workload | 99 | 80 |
RER at end | 1.31 | |
VO2peak (max) (mL/kg/min) | 20.9 | 14.5 (50%) |
VO2 at AT | 7.5 (36%) | |
VE/VCO at AT | 34 | |
Maximum VE, L.min | 118 | 38.2 (32%) |
Breathing Reserve | 67% | |
BP (rest, max) | 110/70; 190/90 | |
ECG (rest, max) | 91; 178 (104%) | |
Vd/Vt | 0.19 – 0.15 | |
VE/VCO2 slope | 32 | |
O2 pulse | 3-4 |
Answer:
Wasserman et al: Chapter 8 refer to the Principles of Interpretation: A flowchart Approach.
Principles of Exercise Testing and Interpretation: including Pathophysiology and Clinical Applications; p. 183.
Referring to flowchart 1 the VO2 is reduced, whereas the anaerobic threshold in normal, which directs us to flowchart 3.
The breathing reserve branch is high and although the ECG is not abnormal, the 9 panel plot directs us the diagnosis of myocardial ischeamia.